Taltz


  • Brands Taltz
  • Product Code: Taltz
  • Taltz works by binding to IL-17A, inhibiting its interaction with the IL-17 receptor. This action reduces the release of proinflammatory cytokines and chemokines, thereby decreasing inflammation associated with autoimmune conditions .Indications

    Taltz is indicated for the treatment of

    • Plaque Psoriasis: Adults and children aged 6 years and older with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

    • Psoriatic Arthritis: Adults with active psoriatic arthritis.

    • Ankylosing Spondylitis: Adults with active ankylosing spondylitis.

    • Non-radiographic Axial Spondyloarthritis: Adults with active non-radiographic axial spondyloarthritis with objective signs of inflammation .

    Administration & Dosing

    Taltz is administered as a subcutaneous injection. The dosing schedule varies based on the condition being treated

    • Plaque Psoriasis:

      • 160 mg at Week 0 (two 80 mg injections), followed by 80 mg at Weeks 2, 4, 6, 8, 10, and 12, then 80 mg every 4 weeks thereafter.

    • Psoriatic Arthritis:

      • 160 mg at Week 0 (two 80 mg injections), followed by 80 mg every 4 weeks thereafter .

    • Ankylosing Spondylitis:

      • 160 mg at Week 0 (two 80 mg injections), followed by 80 mg every 4 weeks thereafter 

    • Non-radiographic Axial Spondyloarthritis:

      • 80 mg every 4 weeks

    Side Effects

    Common side effects of Taltz include:

    • Upper respiratory infections

    • Injection site reactions

    • Headache

    • Fatigue

    • Diarrhea

    • Nausea

    Serious side effects may include:

    • Increased risk of infections

    • Allergic reactions

    • Elevated blood pressure

    • Changes in liver function tests

    Patients should be monitored for signs of infection and other potential adverse effects during treatment .

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